Butler Hospital

1104801349

2023-10-06

View on NPI website

MR. STEPHEN E BURKE

VP OF FINANCE

4014556275

276400000X - Substance Use Disorder Rehabilitation Hospital Unit

No

283Q00000X - Psychiatric Hospital

Yes

324500000X - Substance Abuse Rehabilitation Facility

No

+1 401-455-6200

4014556498

549300W18OGMT5LGDC55

2013-08-22

2014-08-22

LAPSED

FULLY_CORROBORATED

UCC-3 AMENDMENT

202227654530

2022-09-26

DebtorDelete

CARE NEW ENGLAND HEALTH SYSTEM

Debtor(s)

Butler Hospital

Debtor(s)

Women & Infants Hospital of Rhode Island

Debtor(s)

Women & Infants Corporation

Debtor(s)

Kent County Memorial Hospital

Debtor(s)

KENT COUNTY VISITING NURSE ASSOCIATION

Debtor(s)

The Memorial Hospital

Debtor(s)

The Providence Center, Inc.

Debtor(s)

Southeastern Healthcare System, Inc.

Debtor(s)

UCC-3 AMENDMENT

202227654440

2022-09-26

DebtorDelete

The Memorial Hospital

Debtor(s)

The Providence Center, Inc.

Debtor(s)

CARE NEW ENGLAND HEALTH SYSTEM

Debtor(s)

Butler Hospital

Debtor(s)

Women & Infants Hospital of Rhode Island

Debtor(s)

Women & Infants Corporation

Debtor(s)

Kent County Memorial Hospital

Debtor(s)

Southeastern Healthcare System, Inc.

Debtor(s)

KENT COUNTY VISITING NURSE ASSOCIATION

Debtor(s)

UCC-3 AMENDMENT

202227654620

2022-09-26

DebtorDelete

CARE NEW ENGLAND HEALTH SYSTEM

Debtor(s)

Women & Infants Hospital of Rhode Island

Debtor(s)

Women & Infants Corporation

Debtor(s)

Kent County Memorial Hospital

Debtor(s)

KENT COUNTY VISITING NURSE ASSOCIATION

Debtor(s)

Southeastern Healthcare System, Inc.

Debtor(s)

The Memorial Hospital

Debtor(s)

Butler Hospital

Debtor(s)

The Providence Center, Inc.

Debtor(s)

VA24111P9904

View Award on USAspending website

AWARD

PO

Department of Veterans Affairs

2011-09-30

IFG::OT::IFG CLINICAL PSYCHOLOGY TRAINING SERVICES

611310: COLLEGES, UNIVERSITIES, AND PROFESSIONAL SCHOOLS

U099: OTHER ED & TRNG SVCS

VA650C10166

View Award on USAspending website

AWARD

PO

Department of Veterans Affairs

2010-10-01

ACCREDITATION OF PSYCHOLOGY INTERNSHIP PROGRAM AND POSTDOCTORAL RESIDENCY PROGRAM AT VAMC PROVIDENCE RI

622210: PSYCHIATRIC AND SUBSTANCE ABUSE HOSPITALS

AJ63: PSYCHOLOGICAL SCIENCES (ADVANCED)

V650P83741

View Award on USAspending website

AWARD

PO

Department of Veterans Affairs

2008-05-21

VA SHARE OF APA ACCREDIATION FEE FOR PSYCHOLOGY IN

U005: TUITION/REG/MEMB FEES

2025-04-11

View on USAspending

Department of Health and Human Services

AMBULATORY ASSESSMENT OF GLUCOSE REGULATION IN SUICIDAL THOUGHTS AND BEHAVIORS - PROJECT SUMMARY SUICIDE RATES IN THE UNITED STATES ALARMINGLY INCREASED BY 37% IN THE LAST TWO DECADES. DESPITE EXTENSIVE RESEARCH EFFORTS TO IDENTIFY RISK FACTORS, ACCURATE PREDICTION OF SUICIDAL THOUGHTS AND BEHAVIORS (STBS) REMAINS POOR. THERE IS A CRITICAL NEED TO IMPROVE DETECTION OF WHO IS AT GREATEST RISK FOR SUICIDE AND WHEN SUICIDAL CRISES WILL OCCUR TO ENABLE PERSONALIZED AND TIMELY INTERVENTIONS. PASSIVE AMBULATORY MEASUREMENT METHODS THAT CAN DETECT RISK FOR STBS IN DAILY LIFE, WITHOUT RELYING ON PARTICIPANT SELF-REPORTING DURING PERIODS OF DISTRESS, MAY BE THE KEY TO MAKING PROGRESS ON THIS CRITICAL ISSUE. ONE PROMISING STB RISK FACTOR THAT IS AMENABLE TO PASSIVE MONITORING IS PERIPHERAL GLUCOSE (BLOOD SUGAR) REGULATION. PSYCHIATRIC AND METABOLIC DISORDERS ARE HIGHLY COMORBID, AND ROBUST LITERATURE IDENTIFIES ABNORMAL GLUCOSE REGULATION IN INDIVIDUALS WITH STBS. HOWEVER, PRIOR STUDIES OF GLUCOSE REGULATION IN STBS WERE CROSS-SECTIONAL AND RETROSPECTIVE, PREVENTING THE ASSESSMENT OF WHETHER GLUCOSE PATTERNS SIGNAL RISK FOR STBS IN REAL-TIME AND DURING HIGH-RISK PERIODS. THIS K23 PROPOSES TO CONDUCT THE FIRST STUDY EXAMINING HOW AMBULATORY GLUCOSE REGULATION RELATES TO STBS IN DAILY LIFE. WE PROPOSE TO ENROLL 110 NON-DIABETIC ADULT PSYCHIATRIC INPATIENTS WITH RECENT STBS, A POPULATION AND TIME-PERIOD WITH EXTRAORDINARILY HIGH SUICIDE RISK. PARTICIPANTS WILL COMPLETE A MULTIMODAL AMBULATORY ASSESSMENT PROTOCOL FOR 28 DAYS FOLLOWING HOSPITALIZATION, INCLUDING CONTINUOUS GLUCOSE MONITORING AND ECOLOGICAL MOMENTARY ASSESSMENT (EMA). USING STATE-OF-THE-SCIENCE ANALYTIC METHODS FOR MULTIMODAL INTENSIVE LONGITUDINAL DATA, WE WILL EXAMINE PASSIVELY COLLECTED GLUCOSE METRICS AS PROSPECTIVE PREDICTORS OF (1) PROXIMAL SUICIDAL IDEATION (CAPTURED VIA EMA) AND SUICIDAL BEHAVIOR AT FOLLOW-UP (AIM 1), AND (2) PROXIMAL AFFECTIVE-COGNITIVE RISK FACTORS FOR STBS (CAPTURED VIA EMA) AND OVERALL AFFECTIVE-COGNITIVE RISK FACTORS MEASURED AT FOLLOW-UP (AIM 2). WE WILL ALSO EXPLORE POTENTIAL MECHANISMS LINKING GLUCOSE REGULATION TO STBS BY INVESTIGATING IF THESE PATHWAYS VARY ACROSS MODIFIABLE HEALTH BEHAVIORS THAT IMPACT GLUCOSE REGULATION (EXPLORATORY AIM 3). THIS KNOWLEDGE COULD IMPROVE PERSONALIZED STB RISK DETECTION AND INFORM THE DEVELOPMENT OF PRECISION INTERVENTIONS THAT TARGET MODIFIABLE METABOLIC RISK FACTORS FOR SUICIDE. THE CANDIDATE’S TRAINING PLAN DIRECTLY ALIGNS WITH THE PROPOSED STUDY AND WILL PROVIDE IMMERSIVE TRAINING IN (1) DESIGNING AND DIRECTING MULTIMODAL AMBULATORY ASSESSMENT PROTOCOLS; (2) ETHICAL AND REGULATORY ASPECTS OF SUICIDE RESEARCH IN HIGH-RISK SAMPLES; (3) UNDERSTANDING AND ASSESSING METABOLIC RISK FACTORS FOR SUICIDE; (4) ADVANCED ANALYSES FOR MULTIMODAL DATA; AND (5) GRANT-WRITING, LABORATORY MANAGEMENT, AND INTERDISCIPLINARY COLLABORATION. THE CANDIDATE’S TEAM OF INTERDISCIPLINARY MENTORS, DRS. ABRANTES, SCHATTEN, RICHARDSON, TYRKA, AND BRICK, ARE RENOWNED EXPERTS IN THESE TOPICS, AND BUTLER HOSPITAL AND BROWN UNIVERSITY PROVIDE AN EXCEPTIONAL TRAINING ENVIRONMENT WITH AN EXTENSIVE HISTORY OF SUPPORTING CAREER DEVELOPMENT AWARDS. THIS K23 WILL FACILITATE THE CANDIDATE’S SUCCESSFUL TRANSITION TO AN INDEPENDENT RESEARCH CAREER FOCUSED ON ADVANCING SUICIDE PREDICTION AND PREVENTION USING ECOLOGICALLY VALID AND BIOBEHAVIORAL APPROACHES.

201852.00

0.00

0.00

2025-02-03

View on USAspending

Department of Health and Human Services

EVALUATING THE EFFECTIVENESS OF MINDFULNESS-BASED THERAPY FOR SMI IMPLEMENTED IN A COMMUNITY MENTAL HEALTH SETTING - SERIOUS MENTAL ILLNESS (SMI), ENCOMPASSING SCHIZOPHRENIA-SPECTRUM AND MAJOR MOOD DISORDERS, HAS BEEN ESTIMATED TO AFFECT APPROXIMATELY 5.4% OF THE U.S. ADULT POPULATION EACH YEAR. RESEARCH SHOWS LOW RATES OF EVIDENCE-BASED TREATMENT BEING PROVIDED TO PATIENTS WITH SMI. THIS IS UNFORTUNATE, BECAUSE EVIDENCE-BASED PSYCHOLOGICAL THERAPIES HAVE BEEN SHOWN TO BE EFFECTIVE FOR IMPROVING OUTCOMES IN SMI. ONE SUCH EFFICACIOUS PSYCHOLOGICAL INTERVENTION IS MINDFULNESS-BASED THERAPY (MBT), WHICH INTEGRATES MINDFULNESS PRACTICE WITH COGNITIVE-BEHAVIORAL STRATEGIES TO IMPROVE ILLNESS MANAGEMENT. PREVIOUS TRIALS CONDUCTED IN THE UNITED KINGDOM HAVE SHOWN THAT MBT IMPROVES SYMPTOMS AND FUNCTIONING IN COMMUNITY-BASED OUTPATIENTS WITH SMI, INCLUDING IN ROUTINE PRACTICE SETTINGS. IN THE U.S., MOST PATIENTS WITH SMI RECEIVE TREATMENT AT LOCAL COMMUNITY MENTAL HEALTH CENTERS (CMHCS). HOWEVER, PATIENTS IN CMHCS OFTEN CANNOT ACCESS EVIDENCE-BASED THERAPIES LIKE MBT DUE TO THE LACK OF TRAINED STAFF ABLE TO PROVIDE THESE INTERVENTIONS. FURTHER, PREVIOUS STUDIES OF MBT HAVE BEEN CONDUCTED EXCLUSIVELY OUTSIDE THE U.S. IT IS ESSENTIAL TO CONFIRM THAT MBT IS EFFECTIVE WHEN DELIVERED FOR PATIENTS WITH SMI IN THE U.S., AND HOW IT CAN BE SUSTAINABLY IMPLEMENTED IN CMHCS WHERE THIS CLINICAL POPULATION IS COMMONLY TREATED. THUS, WE PROPOSE TO TEST THE EFFECTIVENESS OF MBT FOR SMI AND STUDY ITS IMPLEMENTATION IN A TYPICAL CMHC SETTING. ADDITIONALLY WE WILL SPECIFY A CERTIFIED TRAINING PROGRAM IN MBT FOR FRONTLINE CLINICIANS, GIVEN THE DIFFERENCES BETWEEN U.K. AND U.S. HEALTHCARE SYSTEMS. TO SPEED TRANSLATION TO CLINICAL PRACTICE, WE ALSO WILL COLLECT INFORMATION FROM DIVERSE COMMUNITY PARTNERS ON IMPLEMENTATION BARRIERS AND FACILITATORS TO PROMOTE FUTURE UPTAKE. WE WILL RANDOMIZE 160 PATIENTS WITH SMI (PSYCHOTIC-SPECTRUM AND MAJOR MOOD DISORDERS) TO RECEIVE TREATMENT AS USUAL (TAU) VS TAU PLUS MBT DELIVERED BY FRONTLINE CLINICIANS IN A LARGE, DIVERSE CMHC. WE WILL CONDUCT BLINDED ASSESSMENTS AT BASELINE AND AT 6- (MID), 12- (POST), AND 24- WEEKS (FOLLOW-UP). CONSISTENT WITH AN EXPERIMENTAL THERAPEUTICS APPROACH, WE WILL EXAMINE POTENTIAL MECHANISMS OF ACTION (E.G., MINDFULNESS SKILLS), AS WELL AS COLLECT IMPLEMENTATION-FOCUSED QUANTITATIVE AND QUALITATIVE DATA FROM OUR COMMUNITY PARTNERS (PATIENTS, ADMINISTRATORS, CLINICIANS). IF FOUND TO BE EFFECTIVE AND AIDED BY A CERTIFIED TRAINING PROGRAM AND THE IMPLEMENTATION DATA COLLECTED, MBT COULD BE ADOPTED AS A FUTURE EVIDENCE-BASED PRACTICE AND INTEGRATED INTO THE ROUTINE COMMUNITY CARE OF PATIENTS WITH SMI, THEREBY REDUCING HEALTH DISPARITIES.

768172.00

0.00

0.00

2024-09-23

View on USAspending

Department of Health and Human Services

DEVELOPMENT AND PRELIMINARY TESTING OF A PEER NARRATIVE VIDEO INTERVENTION FOR OLDER ADULTS WITH CHRONIC PAIN - CHRONIC MUSCULOSKELETAL (MSK) PAIN, WHICH INCLUDES SPINAL PAIN, OSTEOARTHRITIS, AND FIBROMYALGIA, IS A COMMON AND COSTLY PROBLEM FOR OLDER ADULTS AND IS ASSOCIATED WITH DECREASED QUALITY OF LIFE. THERE IS A CLEAR NEED FOR INTERVENTIONS THAT INCREASE ONE’S ABILITY TO COPE WITH CHRONIC PAIN AND ENGAGE IN MEANINGFUL LIFE ACTIVITIES EVEN WITH THE PRESENCE OF CHRONIC PAIN. ACCEPTANCE AND COMMITMENT THERAPY (ACT) IS A PSYCHOTHERAPY THAT USES MINDFULNESS AND PSYCHOLOGICAL ACCEPTANCE TO SUPPORT INDIVIDUALS IN WORKING TOWARD BEHAVIORAL GOALS GUIDED BY THEIR PERSONAL VALUES, EVEN IN THE PRESENCE OF UNDESIRABLE EXPERIENCES SUCH AS CHRONIC PAIN. CLINICAL PRACTICE GUIDELINES RECOMMEND THE USE OF ACT FOR TREATING CHRONIC PAIN BASED ON EVIDENCE OF EFFECTIVENESS FROM MULTIPLE RCTS. HOWEVER, UPTAKE AND REACH ARE LIMITED BECAUSE THERE ARE INSUFFICIENT NUMBERS OF MENTAL HEALTH PROFESSIONALS WHO CURRENTLY OFFER ACT OR OTHER RECOMMENDED THERAPIES (E.G., COGNITIVE-BEHAVIORAL THERAPY) FOR CHRONIC PAIN. IN ADDITION, MANY OLDER ADULTS ARE NOT WILLING OR ABLE TO ENGAGE IN TRADITIONAL PSYCHOTHERAPY FOR CHRONIC PAIN EVEN WHEN IT IS AVAILABLE. ALTHOUGH SOME BIBLIOTHERAPY AND DIGITAL HEALTH INTERVENTIONS (E.G., APPS) HAVE BEEN DEVELOPED FOR TREATING PAIN, MANY OLDER ADULTS FAIL TO USE THEM DUE TO LOW LEVELS OF COMFORT WITH TECHNOLOGY OR LACK OF MOTIVATION FOR INTENSIVE SELF-GUIDED APPROACHES. NARRATIVE COMMUNICATION IS AN ALTERNATIVE WAY TO DELIVER BEHAVIOR CHANGE PRINCIPLES THAT INVOLVES “STORYTELLING” INVOLVING REAL PATIENTS TALKING ABOUT THEIR STRUGGLES AND RECOVERY PROGRESS. THERAPEUTIC NARRATIVES DELIVERED VIA VIDEOS MAY BE MORE ENGAGING AND IMMERSIVE THAN TRADITIONAL SELF-HELP FORMATS FOR OLDER ADULTS. IN PREVIOUS GRANT-FUNDED RESEARCH, OUR TEAM HAS DEVELOPED METHODS FOR CREATING NARRATIVE, VIDEO-BASED INTERVENTIONS DESIGNED TO REDUCE DEPRESSION IN PRIMARY CARE PATIENTS AND PREVENT SUICIDE IN PATIENTS FOLLOWING A PSYCHIATRIC HOSPITAL. THUS, IN THIS PROJECT, WE PROPOSE TO CREATE RECLAIM YOUR DAY (RYD), WHICH WILL CONSIST OF 6, 30-MIN WEEKLY VIDEO EPISODES HIGHLIGHTING PATIENTS’ INSPIRING AND ILLUSTRATIVE EXPERIENCES LIVING WITH CHRONIC PAIN IN ORDER TO TEACH CURRENT PATIENTS WITH CHRONIC MSK PAIN HOW TO APPLY ACT’S EVIDENCE-BASED STRATEGIES. IN PHASE 1 OF THIS PROJECT, WE WILL INTERVIEW OLDER ADULTS WITH CHRONIC MSK PAIN ABOUT THEIR COPING HISTORY, AND CODE INTERVIEWS FOR CONSISTENCY WITH ACT PRINCIPLES. WE WILL INVITE A SUBSET OF THESE INDIVIDUALS TO WORK WITH A PROFESSIONAL STORYTELLING COACH TO DEVELOP AND VIDEORECORD THEIR ACT-CONSISTENT STORIES. THESE DOCUMENTARY-STYLE VIDEOS THAT WILL FORM THE BASIS OF RYD. IN PHASE 2, WE WILL CONDUCT A PILOT RCT (N=100) OF OLDER ADULTS WITH CHRONIC MSK PAIN. ALL PARTICIPANTS WILL RECEIVE A 30-MIN INTRODUCTORY PAIN EDUCATION VIDEO. PARTICIPANTS WILL BE RANDOMIZED TO RECEIVE EITHER RYD OR A COMPARISON INTERVENTION (HEALTH EDUCATION VIDEOS). WE WILL EXAMINE RYD FEASIBILITY AND ACCEPTABILITY AS WELL AS CHANGES OVER TIME IN OUTCOMES (PAIN INTERFERENCE, DEPRESSION, QUALITY OF LIFE) AND PUTATIVE MEDIATORS.

421329.00

0.00

0.00

2024-09-23

View on USAspending

Department of Health and Human Services

PILOT MULTISITE RANDOMIZED CONTROLLED TRIAL OF YOGA TO REDUCE DEPRESSION INADOLESCENTS - PROJECT SUMMARY EVEN BEFORE THE ONSET OF THE COVID PANDEMIC, ADOLESCENT DEPRESSION HAS BEEN INCREASING, AND HEALTH DISPAR- ITIES AND DISPARITIES IN ACCESS TO TREATMENT HAVE CONTINUED TO WIDEN. THUS, THERE IS A CLEAR NEED FOR INNOVATIVE, ACCESSIBLE TREATMENTS FOR DEPRESSED ADOLESCENTS, INCLUDING TREATMENTS THAT DO NOT RELY ON A LIMITED POOL OF CHILD AND ADOLESCENT HEALTH PROVIDERS. YOGA-BASED INTERVENTIONS (YBIS) HAVE SHOWN PROMISE FOR ADULT DEPRESSION. SEVERAL ATTRACTIVE ASPECTS OF YOGA INCLUDE ITS: 1) AVAILABILITY THROUGHOUT THE U.S.; 2) ACCESSIBILITY VIA ONLINE CLAS- SES; 3) INDEPENDENCE FROM AN OVERBURDENED MENTAL HEALTH CARE SYSTEM; AND 4) GENERALIZABILITY--YOGA STUDENTS STATE THAT THEY USE MINDFULNESS AND BREATHING PRACTICES TO COPE WITH STRESS IN EVERYDAY LIFE. FUNDED BY A NCCIH R34, WE DEVELOPED A YBI FOR DEPRESSED ADOLESCENTS, AND DEMONSTRATED THAT THIS IN-PERSON PROGRAM WAS ACCEPTABLE AND FEASIBLE IN A SMALL SAMPLE (N=11) OF DEPRESSED ADOLESCENTS AS WELL AS IN A PILOT RCT (N=42) OF YBI VS. AN EXISTING EVIDENCE-BASED TREATMENT, GROUP COGNITIVE-BEHAVIORAL THERAPY (GCBT). THE RCT CLASSES WERE INITIALLY IN-PERSON, BUT WE MIGRATED TO SYNCHRONOUS ONLINE CLASSES DUE TO COVID-19. IN THE RCT, PARTICIPANTS WITHIN EACH STUDY ARM SHOWED DECREASED DEPRESSION SYMPTOMS AND INCREASED SELF-COMPASSION OVER TIME. MOST A PRIORI FEASIBILITY AND ACCEPTABILITY TARGETS WERE MET (E.G., RECRUITMENT, RETENTION, EXPECTANCY, SATISFACTION, CREDIBILITY, ATTENDANCE, AND ADHERENCE). HOWEVER, PARTICIPANTS DID NOT ENGAGE IN HOME (OUTSIDE-OF- CLASS) PRACTICE AT THE TARGETED RATE. THUS, IN THE PRESENT PROPOSAL WE HAVE MODIFIED OUR PROTOCOL TO PROVIDE AN OPPORTUNITY FOR TWICE-WEEKLY SUPERVISED YOGA PRACTICE (ONE IN-PERSON CLASS ON THE WEEKEND, AND ONE VIRTUAL CLASS MIDWEEK). OUR PRIOR PILOT TRIAL WAS BASED AT ONLY ONE SITE (PROVIDENCE RI) WITH ONE PRIMARY YBI INSTRUCTOR AND TWO GCBT LEADERS. MULTIPLE SITES AND INSTRUCTORS/LEADERS, AND RECRUITMENT OF A MORE RACIALLY AND ETHNICALLY DIVERSE SAMPLE, WILL BE IMPORTANT TO DEMONSTRATE GENERALIZABILITY AND TO ENHANCE EFFECTIVENESS. WE NOW PRO- POSE TO CONDUCT A TWO-PHASE MULTI-SITE FEASIBILITY TRIAL. PHASE 1 (N=20) WILL FOCUS ON INCREASING ACCESSIBILITY AND FEASIBILITY OF YBI FOR PARTICULAR GROUPS OF ADOLESCENTS. WE WILL CONDUCT INDIVIDUAL INTERVIEWS WITH TEENS WHO WERE LESS REPRESENTED IN OUR PILOT TRIAL (AFRICAN-AMERICAN/BLACK, ASIAN AMERICAN, AND MALE ADOLESCENTS) TO GAIN THEIR FEEDBACK ON YOGA BASED INTERVENTIONS, WITH A FOCUS ON INCREASING ACCESSIBILITY AND FEASIBILITY FOR ADOLESCENTS WITH THESE IDENTITIES. PHASE 2 (N=128) WILL BE A PILOT RCT OF YBI VS. GCBT AT TWO GEOGRAPHICALLY DISTINCT SITES: BOSTON, MA AND COLUMBUS, OH. GIVEN THE RISING PREVALENCE OF ADOLESCENT DEPRESSION AND THE EXISTENCE OF ESTABLISHED, EFFICACIOUS GROUP TREATMENT FOR DEPRESSION (I.E., GROUP CBT), WE DETERMINED THAT A NON-INFERIORITY TRIAL REPRESENTED THE MOST ETHICAL WAY TO PROCEED. WE WILL INCORPORATE LESSONS LEARNED FROM THIS STUDY TO FURTHER REFINE STUDY MATERIALS AND CREATE A TEMPLATE FOR ONBOARDING MULTIPLE FUTURE SITES. THIS PROJECT WILL PREPARE US TO CONDUCT A MULTISITE, ADEQUATELY POWERED, NON-INFERIORITY RCT OF YBI VS. GCBT IN DEPRESSED ADOLESCENTS.

707778.00

0.00

0.00

2024-11-19

View on USAspending

Department of Health and Human Services

CRANIAL ELECTROTHERAPY STIMULATION: PILOTING A ROAD TO PTSD PREVENTION IN FIRST RESPONDERS - PROJECT SUMMARY THE GOAL OF THE BUTLER HOSPITAL COBRE CENTER FOR NEUROMODULATION PARENT AWARD IS TO SUPPORT INTERDISCIPLINARY CLINICAL-TRANSLATIONAL BRAIN RESEARCH BY CREATING THE KEY INFRASTRUCTURE TO SUPPORT THE CAREERS OF INTERDISCIPLINARY INVESTIGATORS WITH AS OVERALL OBJECTIVE TO ADVANCE THE USE OF NONINVASIVE NEUROMODULATION IN CIRCUIT-BASED THERAPIES FOR NEUROPSYCHIATRIC DISORDERS, INCLUDING POSTTRAUMATIC STRESS DISORDER. IN DOING SO, THE COBRE CENTER FOR NEUROMODULATION ADDRESSES THE PRESSING NEED FOR INNOVATIVE AND EFFECTIVE TREATMENTS FOR PEOPLE STRUGGLING WITH PSYCHIATRIC DISORDERS. THE CURRENT PROPOSAL BUILDS UPON THIS OVERARCHING OBJECTIVE. SPECIFICALLY, THE PROPOSED ADMINISTRATIVE SUPPLEMENT AIMS TO TEST THE FEASIBILITY AND ACCEPTABILITY OF A FOUR-WEEK COURSE OF NONINVASIVE CRANIAL ELECTROTHERAPY STIMULATION (CES) AS WELL AS ESTABLISH AN EARLY SIGNAL OF CES EFFECTS ON HOMEOSTATIC FUNCTIONING IN A SAMPLE OF FIREFIGHTER FIRST RESPONDERS. FIREFIGHTERS ARE AT ULTRA-HIGH RISK FOR DEVELOPING POSTTRAUMATIC STRESS DISORDER DUE TO THE NATURE OF THEIR OCCUPATION WHICH HAS BOTH DIRE PERSONAL AS WELL AS ECONOMIC, WORKFORCE- RELATED CONSEQUENCES. THEREFORE, THERE IS AN URGENT NEED FOR AN EFFECTIVE PREVENTATIVE INTERVENTION FOR POSTTRAUMATIC STRESS DISORDER. THIS IS SCIENTIFICALLY CHALLENGING, AND CURRENT INTERVENTION STRATEGIES THAT AIM TO PREVENT THE DEVELOPMENT OF POSTTRAUMATIC STRESS DISORDER HAVE EITHER HAD LITTLE TO MODEST SUCCESS (E.G., PHARMACOTHERAPY) OR ARE UNREALISTIC TO IMPLEMENT WHEN THE SOURCE OF TRAUMA IS ONE'S OCCUPATION AND THUS UNAVOIDABLE (E.G., PSYCHOTHERAPY). THE REPEATED EXPOSURE TO TRAUMATIC EVENTS REGULARLY FACED BY FIREFIGHTERS PUTS THEM AT RISK FOR HOMEOSTATIC DYSREGULATION, CONTRIBUTING TO THE PATHOGENESIS OF POSTTRAUMATIC STRESS DISORDER. CES IS THOUGHT TO REESTABLISH PHYSIOLOGICAL HOMEOSTASIS, THUS REDUCING THE NEGATIVE CONSEQUENCES OF (REPEATED) TRAUMATIC STRESS. HOWEVER, DESPITE LITERATURE ON CES EFFECTIVENESS TO IMPROVE SYMPTOMS OF ANXIETY, INSOMNIA, AND DEPRESSION, THE MECHANISM OF CES EFFECTS ON HOMEOSTATIC FUNCTIONING REMAINS RATHER HYPOTHETICAL WITH LITTLE DIRECT EVIDENCE TO DATE. IN ADDITION, THE APPLICATION OF CES SHOULD BE CAREFULLY INTEGRATED WITH FIREFIGHTER WORK SCHEDULES. EVEN THOUGH CES CARRIES LITTLE TO NO SIDE EFFECTS AND CAN BE DONE SAFELY OUTSIDE THE CLINIC, ITS USAGE WOULD BE RESTRICTED TO OFF-DUTY DAYS WHICH RAISES IMPORTANT QUESTIONS ABOUT CES FEASIBILITY AND ACCEPTABILITY IN FIREFIGHTERS. ULTIMATELY, THE LONG-TERM GOAL OF THIS LINE OF WORK IS TO DEVELOP AN EFFECTIVE, EASILY DEPLOYABLE, PROACTIVE INTERVENTION TO PREVENT THE DEVELOPMENT OF POSTTRAUMATIC STRESS DISORDER IN FIRST RESPONDERS. TO TEST FEASIBILITY, ACCEPTABILITY, AND EARLY SIGNAL OF CES HOMEOSTASIS, WE HAVE ASSEMBLED A COLLABORATIVE PARTNERSHIP BETWEEN INVESTIGATORS OF THE BUTLER HOSPITAL COBRE FOR NEUROMODULATION AND THE RHODE ISLAND HOSPITAL COBRE ON OPIOIDS AND OVERDOSE. BOTH THE COBRE FOR NEUROMODULATION AND THE COBRE ON OPIOIDS AND OVERDOSE ARE IN RHODE ISLAND WITHIN A 10-MINUTE DRIVING DISTANCE. THIS PROXIMITY PERMITS A CLOSE PARTNERSHIP BETWEEN INVESTIGATORS. THE PROPOSED COMPLIMENTARY AND INTERDISCIPLINARY TEAM WILL LEVERAGE EXPERTISE ON THE PATHOGENESIS OF POSTTRAUMATIC STRESS DISORDER AND METHODOLOGICAL STRENGTHS FROM THE FIELDS OF PSYCHIATRY (DR. FUKUDA), COGNITIVE NEUROPSYCHIATRY (DR. VAN ’T WOUT-FRANK), AND CLINICAL PSYCHOLOGY (DR. WEISS) TO PROPOSE THE USE OF CES AS A NOVEL APPROACH TO POSTTRAUMATIC STRESS DISORDER PREVENTION. DR. FUKUDA, PRINCIPAL INVESTIGATOR ON A PILOT PROJECT SUPPORTED THROUGH THE COBRE CENTER FOR NEUROMODULATION, AND DR. VAN ’T WOUT-FRANK, PROJECT LEADER WITHIN THE COBRE CENTER FOR NEUROMODULATION, PROVIDE THE EXPERTISE IN POSTTRAUMATIC STRESS DISORDER, INFRASTRUCTURE TO SUPPORT THE ADMINISTRATION OF CES AS A NONINVASIVE BRAIN STIMULATION TECHNIQUE, AND IN ASSESSING ITS EFFECTS VIA MEASURING BRAIN ACTIVITY AND (PSYCHO)PHYSIOLOGY, INCLUDING THE STRESS HORMONE CORTISOL AND HEART RAT

11266561.00

0.00

0.00

2022-02-17

Complaint

345 BLACKSTONE BLVD., PROVIDENCE, RI, 02906

Health

Partial

05-0258812

% KATHY TOPOR

Government Instrumentality, Title-Holding Corporation, Charitable Organization, Agricultural Organization, Board of Trade, Pleasure, Recreational, or Social Club, Fraternal Beneficiary Society, Order or Association, Voluntary Employees' Beneficiary Association (Non-Govt. Emps.), Domestic Fraternal Societies and Associations, Teachers Retirement Fund Assoc., Benevolent Life Insurance Assoc., Burial Association, Credit Union, Mutual Insurance Company or Assoc. Other Than Life or Marine, Corp. Financing Crop Operations, Supplemental Unemployment Compensation Trust or Plan, Employee Funded Pension Trust (Created Before 6/25/59), Post or Organization of War Veterans, Legal Service Organization, Black Lung Trust, Multiemployer Pension Plan, Veterans Assoc. Formed Prior to 1880, Trust Described in Sect. 4049 of ERISA, Title Holding Co. for Pensions, etc., State-Sponsored High Risk Health Insurance Organizations, State-Sponsored Workers' Compensation Reinsurance, ACA 1322 Qualified Nonprofit Health Insurance Issuers, Apostolic and Religious Org. (501(d)), Cooperative Hospital Service Organization (501(e)), Cooperative Service Organization of Operating Educational Organization (501(f)), Child Care Organization (501(k)), Charitable Risk Pool, Qualified State-Sponsored Tuition Program, 4947(a)(1) - Private Foundation (Form 990PF Filer)

1919-08

Type of organization and use of contribution: A public charity. Deductibility Limitation: 50% (60% for cash contributions)

2023-05-24

Pending

Missing

Both plaintiff and defendant demand jury

Medical Malpractice

DESCHENE

Plaintiff

Butler Hospital

Defendant

2012-03-09

Terminated

no monetary award

Both plaintiff and defendant demand jury

Medical Malpractice

HYMAN

Plaintiff

Butler Hospital

Defendant

1995-06-23

Missing

Missing

Civil Rights Accommodations

DOE

Plaintiff

Butler Hospital

Defendant